Circulating in Belgium and Rotaviruses in RotarixTM
نویسندگان
چکیده
Genetic Analyses Reveal Differences in the VP7 and 1 VP4 Antigenic Epitopes between Human Rotaviruses 2 Circulating in Belgium and Rotaviruses in RotarixTM and 3 RotaTeqTM 4 5 Mark Zeller, John T. Patton, Elisabeth Heylen, Sarah De Coster, 6 Max Ciarlet, Marc Van Ranst, Jelle Matthijnssens 7 8 Laboratory of Clinical and Epidemiological Virology, Department of Microbiology 9 and Immunology, Rega Institute for Medical Research, University of Leuven, 10 Leuven, Belgium; Laboratory of Infectious Diseases, National Institute of Allergy 11 and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA; 12 Clinical Research and Development, Novartis Vaccines & Diagnostics, Inc, 13 Cambridge, Massachusetts, USA 14 15
منابع مشابه
Comparative analysis of the RotarixTM vaccine strain and G1P[8] rotaviruses detected before and after vaccine introduction in Belgium
G1P[8] rotaviruses are responsible for the majority of human rotavirus infections worldwide. The effect of universal mass vaccination with rotavirus vaccines on circulating G1P[8] rotaviruses is still poorly understood. Therefore we analyzed the complete genomes of the RotarixTM vaccine strain, and 70 G1P[8] rotaviruses, detected between 1999 and 2010 in Belgium (36 before and 34 after vaccine ...
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تاریخ انتشار 2011